| # | Equip | PJ | PG | PE | PP | DG | G | Pts | FORMA |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Philadelphia Union | 34 | 20 | 6 | 8 | 22 | 57 | 66 | |
| 2 | Inter Miami | 34 | 19 | 8 | 7 | 26 | 81 | 65 | |
| 3 | Cincinnati | 34 | 20 | 5 | 9 | 12 | 52 | 65 | |
| 4 | Vancouver Whitecaps | 34 | 18 | 9 | 7 | 28 | 66 | 63 | |
| 5 | San Diego | 34 | 19 | 6 | 9 | 23 | 64 | 63 | |
| 6 | Los Angeles | 34 | 17 | 9 | 8 | 25 | 65 | 60 | |
| 7 | Charlotte | 34 | 19 | 2 | 13 | 9 | 55 | 59 | |
| 8 | Minnesota United | 34 | 16 | 10 | 8 | 17 | 56 | 58 | |
| 9 | NY City | 34 | 17 | 5 | 12 | 6 | 50 | 56 | |
| 10 | Seattle Sounders | 34 | 15 | 10 | 9 | 10 | 58 | 55 | |
| 11 | Nashville | 34 | 16 | 6 | 12 | 13 | 58 | 54 | |
| 12 | Columbus Crew | 34 | 14 | 12 | 8 | 4 | 55 | 54 | |
| 13 | Orlando City | 34 | 14 | 11 | 9 | 12 | 63 | 53 | |
| 14 | Chicago Fire | 34 | 15 | 8 | 11 | 8 | 68 | 53 | |
| 15 | Austin | 34 | 13 | 8 | 13 | -8 | 37 | 47 | |
| 16 | Dallas | 34 | 11 | 11 | 12 | -3 | 52 | 44 | |
| 17 | Portland Timbers | 34 | 11 | 11 | 12 | -7 | 41 | 44 | |
| 18 | New York Red Bulls | 34 | 12 | 7 | 15 | 1 | 48 | 43 | |
| 19 | San Jose Earthquakes | 34 | 11 | 8 | 15 | -3 | 60 | 41 | |
| 20 | Salt Lake | 34 | 12 | 5 | 17 | -11 | 38 | 41 | |
| 21 | Colorado Rapids | 34 | 11 | 8 | 15 | -12 | 44 | 41 | |
| 22 | Houston Dynamo | 34 | 9 | 10 | 15 | -13 | 43 | 37 | |
| 23 | New England Revolution | 34 | 9 | 9 | 16 | -7 | 44 | 36 | |
| 24 | Toronto | 34 | 6 | 14 | 14 | -7 | 37 | 32 | |
| 25 | St. Louis City | 34 | 8 | 8 | 18 | -14 | 44 | 32 | |
| 26 | LA Galaxy | 34 | 7 | 9 | 18 | -20 | 46 | 30 | |
| 27 | Sporting Kansas City | 34 | 7 | 7 | 20 | -24 | 46 | 28 | |
| 28 | Atlanta United | 34 | 5 | 13 | 16 | -25 | 38 | 28 | |
| 29 | Montreal Impact | 34 | 6 | 10 | 18 | -26 | 34 | 28 | |
| 30 | DC United | 34 | 5 | 11 | 18 | -36 | 30 | 26 |
Les alineacions inicials confirmades indiquen que Inter Miami juga amb un 4-4-2 i DC United, amb un 4-3-3.
L’onze inicial anunciat de Inter Miami: Oscar Ustari, Marcelo Weigandt, Gonzalo Luján, Maximiliano Falcón, Noah Allen, Rodrigo De Paul, Sergio Busquets, Yannick Bright, Jordi Alba, Lionel Messi i Tadeo Allende.
L’onze inicial anunciat de DC United: Luis Barraza, William Antley, Lucas Bartlett, Kye Rowles, David Schnegg, Gabriel Pirani, Brandon Servania, Jackson Hopkins, Aarón Herrera, Christian Benteke i João Peglow.
En aquesta pàgina: Alineacions, Estadístiques, Comparativa, Classificació
Pàgines relacionades: Inter Miami, DC United, Major League Soccer, Inter Miami - DC United: cara a cara, Resultats de futbol en directe
Resultat final: Inter Miami 3-2 DC United.
Gols per a Inter Miami: Tadeo Allende 35′, Lionel Messi 66′ i 85′. Gols per a DC United: Christian Benteke 52′, Jacob Murrell 90+7′.
diumenge, 21 de setembre del 2025, a les 01:40 (hora peninsular).
Chase Stadium, Fort Lauderdale. L'estadi té capacitat per a 21.550 espectadors.
L'àrbitre del partit va ser Ismir Pekmic.
| Posició | Equip | PJ | DG | Pts |
|---|---|---|---|---|
| 1 | Philadelphia Union | 34 | +22 | 66 |
| 2 | Inter Miami | 34 | +26 | 65 |
| 3 | Cincinnati | 34 | +12 | 65 |
| 29 | Montreal Impact | 34 | -26 | 28 |
| 30 | DC United | 34 | -36 | 26 |